Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation
S. Schumacher, Max Fernkorn, Michelle Marten, Rui Chen, Yung Su Kim, Ivan Bedzhov, Christian J. Schröter
The paper shows that Wnt signaling within the visceral endoderm restricts AVE differentiation, independent of BMP gradients, using mouse stem cell aggregates.
Nature Communications · Jun 13, 2024Peer-reviewedDevelopmental Biology