A universal, genome-wide guide finder for CRISPR/Cas9 targeting in microbial genomes
Michelle Spoto, Elizabeth Fleming, Julia Oh
Guide Finder is a tool that designs CRISPR/Cas9 guides for any bacterial genome, achieving 95% guide design success and demonstrating functional utility in staphylococcal essential gene knockdown.
bioRxiv · Sep 27, 2017 · PreprintMicrobiology