Author

Elizabeth Fleming

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Organism:rat· 1

Frequent Co-Authors

Court HulliD· 1 shared Julia Oh· 1 shared Michelle Spoto· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 1 mutual co-author link

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1 shared paperNeuroscience

Court HullORCID

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2 papers

Recent·Most cited

Serotonin regulates dynamics of cerebellar granule cell activity by modulating tonic inhibition

Elizabeth Fleming, Court Hull

This study shows serotonin increases tonic inhibition of cerebellar granule cells by modulating Golgi cells, reducing spike probability without altering spike timing.

Journal of Neurophysiology · Oct 3, 2018Peer-reviewedNeuroscience

A universal, genome-wide guide finder for CRISPR/Cas9 targeting in microbial genomes

Michelle Spoto, Elizabeth Fleming, Julia Oh

Guide Finder is a tool that designs CRISPR/Cas9 guides for any bacterial genome, achieving 95% guide design success and demonstrating functional utility in staphylococcal essential gene knockdown.

bioRxiv · Sep 27, 2017 · PreprintMicrobiology