Microbiome-TP53 Gene Interaction in Human Lung Cancer
K. Leigh Greathouse, James R. White, Ashely J. Vargas, Valery V. Bliskovsky, Jessica A. Beck, Natalia von Muhlinen, Eric C. Polley, Elise D. Bowman, Mohammed A. Khan, Ana I. Robles, Tomer Cooks, Bríd M. Ryan, Amiran H. Dzutsev, Giorgio Trinchieri, Marbin A. Pineda, , Curtis C. Harris
This study identifies a microbiome-TP53 interaction in squamous cell lung cancer, showing Acidovorax enrichment in smokers with TP53 mutations.
bioRxiv · Feb 28, 2018 · PreprintCancer Biology