Active-like structure of the ligand-binding domain of GluK2 with L-glutamate and the positive allosteric modulator BPAM344
Yasmin Bay, Mie Egeberg Jeppesen, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Darryl S. Pickering, Anders S. Kristensen, J.S. Kastrup
The paper presents a dimeric crystal structure of GluK2's ligand-binding domain with L-glutamate and BPAM344, revealing insights into modulation mechanisms.
bioRxiv · Nov 2, 2023 · PreprintNeuroscience