Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPS cells
Kai Fu, Constantinos Chronis, Abdenour Soufi, Giancarlo Bonora, Miguel Edwards, Stephen T. Smale, Kenneth S. Zaret, Kathrin Plath, Matteo A. Pellegrini
This study compares OSKM reprogramming factor binding in human and mouse fibroblasts, finding conserved mechanisms and species-specific differences in target sites and regulatory networks.
bioRxiv · Nov 27, 2017 · PreprintGenomics