Survivin Promotes the Formation of a Microtubule-Based Glycolytic Hub
Jacob Neumann, Wen-Hsuan Chang, Sarah E. Ackermann, Matthew R. Zanotelli, Tomer Markovich, 杨闰英, Jolie R. Lefkowitz, Shun Enomoto, Henry H. Le, Min-Ting Lee, Kirsten L. Bryant, Richard A. Cerione, Marc A. Antonyak
This study identifies Survivin as a critical KRAS signaling partner that promotes glycolytic activity in PDAC cells by forming microtubule-based complexes with glycolytic enzymes.
bioRxiv · Oct 23, 2026 · PreprintCancer Biology