From Lipid Dynamics to Precision Predictions: A New Approach Methodology for Precision Modeling of Phosphoinositide Signaling
Gonzalo Hernandez-Hernandez, Mindy Tieu, Pei‐Chi Yang, Oscar Vivas, Timothy J. Lewis, Luis Fernando Santana, Colleen E. Clancy
This paper develops a new methodology to model phosphoinositide signaling dynamics, showing that basal PI(4)P levels determine cell-specific responses to genetic perturbations.
The Journal of Precision Medicine Health and Disease · Jul 16, 2026Peer-reviewedBiophysics