Author

Timothy J. Lewis

University of California, DavisORCID 0000-0003-1885-746XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Colleen E. ClancyiD· 2 shared Gonzalo Hernandez-HernandeziD· 1 shared Igor V. VorobyoviD· 1 shared Jon T. SackiD· 1 shared Kazuharu FurutaniiD· 1 shared Khoa NgoiD· 1 shared Luis Fernando SantanaiD· 1 shared Matthew James MarquisiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Colleen E. ClancyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsThe Journal of Precision Medicine Health and DiseasePeer-reviewedJul 16, 2026

From Lipid Dynamics to Precision Predictions: A New Approach Methodology for Precision Modeling of Phosphoinositide Signaling

Gonzalo Hernandez-Hernandez, Mindy Tieu, Pei‐Chi Yang…·Colleen E. Clancy

This paper develops a new methodology to model phosphoinositide signaling dynamics, showing that basal PI(4)P levels determine cell-specific responses to genetic perturbations.

1 citation

humanproteomics

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintJun 3, 2026

A hERG Blocker Facilitates K+ Channel Current by Agonizing Pore Opening while Blocking

Steffen S. Docken, Matthew James Marquis, Khoa Ngo…·Jon T. Sack

The paper investigates how hERG blockers like nifekalant can increase K+ channel current through an agonism-while-blocking mechanism, potentially explaining their safety profile.

DOI 10.64898/2026.05.30.728541

humanelectronic health records

𝕏 PostBluesky