ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress
Yu‐Ching Teng, Aishwarya Sundaresan, Ryan A. O’Hara, Vincent Ulysses Gant, Minhua Li, Sara Martire, Jane N. Warshaw, Amrita B Basu, Laura A. Banaszynski
This study shows ATRX prevents G-quadruplex DNA stress by interacting with the MCM complex and promoting heterochromatin formation via ESET.
Nature Communications · Jun 23, 2021Peer-reviewedMolecular Biology