Structural Basis of Electron Transfer by the Human Nitric Oxide Synthase Holoenzyme Complex
Kanghyun Lee, Cristian Martinez-Ramos, Thomas H. Pospiech, Eric Tse, Miranda Lau, Yoichi Osawa, Daniel R. Southworth
This study reveals the structural basis of electron transfer in the human inducible NOS holoenzyme complex using cryo-EM, showing how cofactors are arranged for catalysis.
bioRxiv · Apr 7, 2026 · PreprintBiochemistry