The Mus musculus papillomavirus type 1 E7 protein binds to the retinoblastoma tumor suppressor - implications for viral pathogenesis
Tao Wei, Miranda R. Grace, Aayushi Uberoi, James C. Romero-Masters, Denis Lee, Paul F. Lambert, Karl Münger
This paper shows that the MmuPV1 E7 protein binds RB1 without using the canonical LXCXE motif and that this interaction is essential for papilloma formation in mice.
mBio · Aug 31, 2021Peer-reviewedMolecular Biology