Author

Denis Lee

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Paul F. LambertiD· 3 shared Aayushi UberoiiD· 1 shared Alan C. Rapraeger· 1 shared Allen J. YorkiD· 1 shared Andrea BilgeriD· 1 shared Cameron C. DurfeeiD· 1 shared DeannaLee M. Beauvais· 1 shared Ella T. Ward-ShawiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

Paul F. LambertORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mus Musculus papillomavirus MmuPV1 resists restriction by human APOBEC3B

Xingyu Liu, Andrea Bilger, Denis Lee, Prokopios P. Argyris, Jiarui Chen, Ella T. Ward-Shaw, Emilia Barreto-Durán, Yu-Hsiu Tony Lin, Cameron C. Durfee, Sang H. Chun, Mahmoud Abdel-Aziz Ibrahim, Joshua Proehl, Allen J. York, Paul F. Lambert, Reuben S. Harris

This study shows human APOBEC3B does not restrict murine papillomavirus MmuPV1 replication in cellulo or in vivo, suggesting papillomaviruses have evolved mechanisms to evade this antiviral factor.

Journal of Virology · Feb 11, 2026Peer-reviewedMicrobiology

The Mus musculus papillomavirus type 1 E7 protein binds to the retinoblastoma tumor suppressor - implications for viral pathogenesis

Tao Wei, Miranda R. Grace, Aayushi Uberoi, James C. Romero-Masters, Denis Lee, Paul F. Lambert, Karl Münger

This paper shows that the MmuPV1 E7 protein binds RB1 without using the canonical LXCXE motif and that this interaction is essential for papilloma formation in mice.

mBio · Aug 31, 2021Peer-reviewedMolecular Biology

MST1R/RON and EGFR in a complex with syndecans sustain carcinoma S-phase progression by preventing p38MAPK activation

DeannaLee M. Beauvais, Kristin Short, Noah Stueven, Scott E. Nelson, Denis Lee, Oisun Jung, Richard A. Anderson, Paul F. Lambert, Alan C. Rapraeger

The paper shows that MST1R/RON and EGFR form a complex with syndecans that prevents p38MAPK activation, sustaining S-phase progression in carcinoma cells by inhibiting DNA replication stress.

bioRxiv · Jan 24, 2018 · PreprintCancer Biology