Author

Miriam Silverstein

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail R. Lambert· 1 shared Barry L. StoddardiD· 1 shared David R. EdgelliD· 1 shared Janet M. YoungiD· 1 shared Lindsey DoyleiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Abigail R. Lambert

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1 paper

Recent·Most cited

The activity, divergence, and evolutionary degradation of modern-day homing endonucleases and their reconstructed ancestors

Janet M. Young, Abigail R. Lambert, Lindsey Doyle, Miriam Silverstein, David R. Edgell, Barry L. Stoddard

The paper analyzes homing endonuclease genes, identifies their activity levels, and reconstructs ancestral forms showing improved function and structural insights.

bioRxiv · Jul 14, 2026 · PreprintBiochemistry