mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation and translational regulation
Caroline A. McCormick, Michele Meseonznik, Yuchen Qiu, Oleksandra Fanari, Mitchell Thomas, Yifang Liu, Dylan Bloch, Isabel N. Klink, Miten Jain, Meni Wanunu, Sara H. Rouhanifard
The paper maps pseudouridylation sites in human cell lines using nanopore sequencing and shows how psi modifications affect translation through distinct mechanisms.
bioRxiv · May 8, 2024 · PreprintGenomics