Michele Meseonznik

The paper compares pseudouridine modification sites in primary and immortalized human T cells using direct RNA sequencing, finding most sites are conserved with some cell-type specific differences.

The paper maps pseudouridylation sites in human cell lines using nanopore sequencing and shows how psi modifications affect translation through distinct mechanisms.

This study uses direct RNA sequencing to examine pseudouridylation dynamics in neurons under healthy and unhealthy conditions, finding changes in psi writer expression and site occupancy.