Flotillin-2 dampens T cell antigen-sensitivity and functionality
Sookjin Moon, Fei Zhao, Mohammad N. Uddin, Charles J. Tucker, Peer W. F. Karmaus, Michael B. Fessler
This study shows that Flotillin-2 reduces T cell sensitivity to weak antigen stimulation by regulating TCR clustering and signaling.
JCI Insight · Nov 5, 2024Peer-reviewedImmunology