A map of RBP-miRNA regulatory connections for deciphering the mechanisms of transcriptome remodeling in cancer
Gabrielle Perron, Mohan Amaravadi, Cynthia Tseng, Pouria Jandaghi, Elham Moslemi, Tamiko Nishimura, Maryam Rajaee, Rached Alkallas, Bruce Culbertson, Kristle Garcia, Ian R. Watson, Hani Goodarzi, Thomas F. Duchaîne, Yasser Riazalhosseini, Hamed Shateri Najafabadi
The paper maps regulatory connections between RBPs and miRNAs in cancer, showing RBP-driven regulation contributes to miRNA activity heterogeneity and identifies DDX55 as a key regulator of miR-29-3p.
bioRxiv · Oct 6, 2026 · PreprintGenomics