Thomas F. Duchaîne

The paper maps regulatory connections between RBPs and miRNAs in cancer, showing RBP-driven regulation contributes to miRNA activity heterogeneity and identifies DDX55 as a key regulator of miR-29-3p.

This study identifies EDC-3 and EDC-4 as regulators of mRNA decay and biomolecular condensate specialization during C. elegans embryonic development.

The paper maps human nuclear bodies using proximity proteomics, identifying new components and regulatory functions in RNA regulation.

The paper shows that AMPK regulates small RNA pathways in somatic cells to control germline stem cell quiescence during energy stress in C. elegans.