A statistical framework for the robust detection of hidden variation in single cell transcriptomes
Donghyung Lee, Anthony Cheng, Mohan Bolisetty, Duygu Ucar
This paper introduces IA-SVA, a method to detect hidden variation in scRNA-seq data, showing it captures technical and biological sources and improves clustering of cell subsets.
bioRxiv · Apr 24, 2018 · PreprintBioinformatics