Author

Molly Magarotto

University of York

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:trajectory inference· 1

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Andrew S. MasoniD· 1 shared Gabriele VilkaiteiD· 1 shared Han-Jou CheniD· 1 shared Marcello Beltrami· 1 shared Richard T. GawneiD· 1 shared

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2025-2025 · peak 1/yr

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Andrew S. MasonORCID

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1 paper

Recent·Most cited

Familial ALS/FTD-associated RNA-Binding deficient TDP-43 mutants cause neuronal and synaptic transcript dysregulation in vitro

Molly Magarotto, Richard T. Gawne, Gabriele Vilkaite, Marcello Beltrami, Andrew S. Mason, Han-Jou Chen

This study shows that RNA-binding deficient TDP-43 mutations in cell models disrupt neuronal differentiation and synaptic pathways, affecting transcriptomic profiles and neurite morphology.

Human Molecular Genetics · Jun 18, 2025Peer-reviewedNeuroscience