Index-agnostic oblique plane light sheet microscopy of centimetre-scale cleared tissues at subcellular resolution
Jacob R. Lamb, Miguel Cardoso Mestre, Ksena Fenwyn Longrin, Pratiksha Bhat, Molly Stevenson, Anna D. Y. Rhodes, Joanna Gosieniecka, Leah C. Redmond, Claire A. Higgins, Noé Rodríguez‐Rodríguez, Madeline A. Lancaster, James D. Manton
This paper introduces CtDvOPM, a microscopy technique that enables high-resolution imaging of large cleared tissues at subcellular levels without image tiling.
bioRxiv · Jun 24, 2026 · PreprintBiophysics