James D. Manton

This paper introduces CtDvOPM, a microscopy technique that enables high-resolution imaging of large cleared tissues at subcellular levels without image tiling.

This paper introduces a method combining single-molecule light-field microscopy with widefield Fourier light-field microscopy to improve volumetric subcellular imaging and molecular diffusion analysis.

The paper introduces a method to improve deep imaging of expanded tissues using inverted microscopes by using FEP film and water immersion objectives, achieving sub-micron resolution and 800 µm depth.

The paper introduces a multispectral imaging approach for live-cell imaging, enabling accurate unmixing of low signal-to-noise ratio data at video rates.

The paper introduces SWIFT, a new interferometer that projects arbitrary interference patterns using a single galvanometric mirror, and applies it to 2D and 3D Structured Illumination Microscopy.

The paper introduces a deconvolution method to reconstruct properly sampled volumes from apparently undersampled oblique plane microscopy data, improving upon a previous Fourier-stitching approach.

This paper demonstrates that controlled aliasing in oblique plane microscopy can increase acquisition speed without loss of resolution or artifacts, enabling faster subcellular 3D imaging of mitochondrial dynamics.

This paper introduces a direct-view oblique plane microscopy technique for mesoscopic imaging, achieving efficient light collection and demonstrating imaging of a brain organoid.

This study shows that intra-mitochondrial proteostasis influences alpha-synuclein and Aβ42 aggregation, while mitochondrial stress factors like complex I inhibition do not affect these pathologies.

The natverse provides an open-source R package suite for analyzing neuroanatomical data, enabling analysis, visualization, and comparison across neuronal datasets.

The paper identifies 165 cell types in the Drosophila lateral horn and shows that 33 of them have stereotyped odor responses, revealing principles of odor categorization in a higher olfactory center.

NBLAST is a tool for comparing neuronal structures and clustering neurons, identifying new types and features in Drosophila datasets.