Jacob R. Lamb

This paper introduces CtDvOPM, a microscopy technique that enables high-resolution imaging of large cleared tissues at subcellular levels without image tiling.

The paper introduces a method to improve deep imaging of expanded tissues using inverted microscopes by using FEP film and water immersion objectives, achieving sub-micron resolution and 800 µm depth.

The paper introduces a deconvolution method to reconstruct properly sampled volumes from apparently undersampled oblique plane microscopy data, improving upon a previous Fourier-stitching approach.

This paper introduces a direct-view oblique plane microscopy technique for mesoscopic imaging, achieving efficient light collection and demonstrating imaging of a brain organoid.

This paper develops a high-resolution microscopy method for imaging live biological samples at sub-zero temperatures to study cold-adapted species under physiological conditions.

This paper demonstrates the localization of nucleic-acid cleaving enzyme activity within DNA-based membrane-less compartments, enabling spatially organized enzymatic reactions and dynamic pattern formation.