Regulation of a Classical Allosteric Molecular Machine by an Intrinsically Disordered Domain: the C-termini of GroEL
Morgan E. Powers, Kacie A. Evans, He Sun, David H. Russell, Hays S. Rye
This study investigates how the intrinsically disordered C-terminal tails of GroEL regulate its allosteric behavior through conformational constraints and interactions with GroES.
bioRxiv · Sep 2, 2026 · PreprintBiophysics