An extended structure of the intracellular domain of the Torpedo nicotinic acetylcholine receptor and its proposed interactions with rapsyn
Camille M. Hénault, Moustafa Habes, Christian J. G. Tessier, John E. Baenziger
The paper refines a cryo-EM structure of the Torpedo nAChR intracellular domain and uses it to evaluate AlphaFold3 models, revealing a 3:1 rapsyn binding architecture and its role in receptor clustering.
bioRxiv · Dec 4, 2025 · PreprintNeuroscience