RNA Stores Tau Reversibly in Complex Coacervates
X. Zhang, Y. Lin, N. A. Eschmann, H. Zhou, J. Rauch, I. Hernandez, E. Guzman, K. S. Kosik, S. Han
This paper shows tau protein forms liquid droplets with RNA, specifically tRNAs, through complex coacervation, and prolonged droplet residency can lead to beta-sheet formation and aggregation.
bioRxiv · May 7, 2017Biophysics