Author

N. A. McCracken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

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Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Wijeratne· 2 shared A. L. Mosley· 2 shared A. M. Runnebohm· 1 shared H. Liu· 1 shared H. S. Wijeratne· 1 shared J. F. Victorino· 1 shared K. A. Staschke· 1 shared S. A. Peck Justice· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

A. B. Wijeratne

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2 papers

Recent·Most cited

Obtaining Increased Functional Proteomics Insights from Thermal Proteome Profiling through Optimized Melt Shift Calculation and Statistical Analysis

N. A. McCracken, H. Liu, A. M. Runnebohm, H. S. Wijeratne, A. B. Wijeratne, K. A. Staschke, A. L. Mosley

This study improves the InflectSSP pipeline for Thermal Proteome Profiling to enhance sensitivity and specificity in detecting proteome changes, demonstrating its effectiveness through reanalysis of datasets and a new UPR study.

bioRxiv · Dec 30, 2022 · PreprintBiophysics

Boosting detection of low abundance proteins in thermal proteome profiling experiments by addition of an isobaric trigger channel to TMT multiplexes

S. A. Peck Justice, N. A. McCracken, J. F. Victorino, A. B. Wijeratne, A. L. Mosley

The paper introduces an isobaric trigger channel in TMT multiplexes to improve detection of low abundance proteins in thermal proteome profiling, enhancing detection of CPF subunits without affecting Tm calculations.

bioRxiv · Dec 30, 2020Biochemistry