Electrostatic encoding of genome organization principles within single native nucleosomes
S. Park, A. Athreya, G. Carrizo, N. Benning, M. Mitchener, N. Bhanu, B. Garcia, B. Zhang, T. W. Muir, E. Pearce, T. Ha
This study shows that single nucleosomes encode A/B compartment information through biophysical properties, specifically condensability, which correlates with gene expression and is electrostatic in nature.
bioRxiv · Dec 8, 2023Biophysics