Author

E. Pearce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Athreya· 1 shared A. Gras· 1 shared A. R. Niedecken· 1 shared A. Regev· 1 shared A. Schnell· 1 shared A. T. Ramjag· 1 shared A. V. Medina-Cucurella· 1 shared A. Wagner· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiophysics

A. Athreya

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Electrostatic encoding of genome organization principles within single native nucleosomes

S. Park, A. Athreya, G. Carrizo, N. Benning, M. Mitchener, N. Bhanu, B. Garcia, B. Zhang, T. W. Muir, E. Pearce, T. Ha

This study shows that single nucleosomes encode A/B compartment information through biophysical properties, specifically condensability, which correlates with gene expression and is electrostatic in nature.

bioRxiv · Dec 8, 2023Biophysics

Capturing and Recreating Diverse Antibody Repertoires as Multivalent Recombinant Polyclonal Antibody Drugs

S. M. Keating, R. A. Mizrahi, M. S. Adams, M. A. Asensio, E. Benzie, K. P. Carter, Y. Chiang, R. C. Edgar, B. K. Gautam, A. Gras, J. Leong, R. Leong, Y. W. Lim, V. A. Manickam, A. V. Medina-Cucurella, , E Meyer

This paper demonstrates a technology to capture and recreate diverse antibody repertoires as multivalent recombinant drugs, showing applications against SARS-CoV-2, Zika virus, and graft-versus-host disease.

bioRxiv · Aug 5, 2020 · PreprintImmunology

Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway

C. Wang, A. Wagner, J. Fessler, J. Avila-Pacheco, J. Karminski, P. Thakore, S. Zaghouani, K. Pierce, L. Bod, A. Schnell, D. DeTomaso, N. Ron-Harel, M. Haigis, D. Puleston, E. Pearce, , V. Kuchroo

The paper identifies the polyamine pathway as a regulator of Th17/Treg balance, showing its impact on inflammation and T cell phenotype.

bioRxiv · Jan 23, 2020 · PreprintImmunology