HOXB8 counteracts MAPK/ERK oncogenic signaling in a chicken embryo model of neoplasia
A. WILMERDING, L. BOUTEILLE, L. RINALDI, N. CARUSO, Y. Graba, M.-C. DELFINI
The paper investigates HOXB8's role in counteracting ERK/MEK oncogenic signaling in a chicken embryo neoplasia model, showing it acts as a tumor suppressor by reversing the oncogenic transcriptome.
bioRxiv · Jun 11, 2021Cancer Biology