Multistage activity within a diverse set of epi-drugs against Plasmodium falciparum parasites
N. Coetzee, H. von Gruning, M. van der Watt, J. Reader, L.-M. Birkholtz
The paper evaluates 95 epigenetic modulators for activity against different stages of Plasmodium falciparum, finding some compounds effective against multiple stages and with transmission-blocking potential.
bioRxiv · Jul 4, 2019 · PreprintBiochemistry