Author

N. D. P. Cosford

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Chaikuad· 1 shared A. Stolz· 1 shared C. H. Brandts· 1 shared C. Pohl· 1 shared H. Ren· 1 shared K. Zivkovic· 1 shared L. J. Lambert· 1 shared S. E. Koschade· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

A. Chaikuad

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1 paper

Recent·Most cited

BiochemistrybioRxivFeb 14, 2019

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

A. Chaikuad, S. E. Koschade, A. Stolz…·S. Knapp

The paper presents the crystal structure of ULK2 with ATP inhibitors, identifies off-target effects of ULK1 inhibitors, and suggests structural insights for developing dual ULK1/2 inhibitors.

DOI 10.1042/bcj20190038

humanprotein structure

𝕏 PostBluesky