Author

C. H. Brandts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Chaikuad· 1 shared A. Stenzinger· 1 shared A. Stolz· 1 shared B. Obermayer· 1 shared C. Messerschmidt· 1 shared C. Pohl· 1 shared D. Beule· 1 shared D. T. Rieke· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Chaikuad

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Author profile →

2 papers

Recent·Most cited

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC

C. Messerschmidt, B. Obermayer, K. Klinghammer, S. Ochsenreither, D. Treue, A. Stenzinger, H. Glimm, S. Fröhling, T. Kindler, C. H. Brandts, K. Schulze-Osthoff, W. Weichert, I. Tinhofer, F. Klauschen, U. Keilholz, , D. T. Rieke

The paper identifies an APOBEC-enriched subgroup of HPV-negative HNSCC with distinct immunogenic features linked to immune evasion and potential response to immunotherapy.

bioRxiv · Mar 28, 2019Cancer Biology

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

A. Chaikuad, S. E. Koschade, A. Stolz, K. Zivkovic, S. Shaid, C. Pohl, H. Ren, L. J. Lambert, N. D. P. Cosford, C. H. Brandts, S. Knapp

The paper presents the crystal structure of ULK2 with ATP inhibitors, identifies off-target effects of ULK1 inhibitors, and suggests structural insights for developing dual ULK1/2 inhibitors.

bioRxiv · Feb 14, 2019Biochemistry