The non-muscle actinopathy-associated mutation E334Q in cytoskeletal gamma-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins
J. N. Greve, A. Marquardt, R. Heiringhoff, T. Reindl, C. Thiel, N. Di Dinato, M. H. Taft, D. J. Manstein
This study characterizes the mutation E334Q in gamma-actin, showing it affects interactions with myosin and ADF/cofilin proteins, potentially contributing to non-muscle actinopathy.
bioRxiv · Sep 10, 2023 · PreprintBiochemistry