N. F. Reuel

Single-use, Metabolite Absorbing, Resonant Transducer (SMART) culture vessels for label-free, continuous cell culture progression monitoring

The paper introduces a continuous metabolite monitoring system using SMART vessels to track cell growth and drug responses in real-time.

Reinforcement learning-guided control strategies for CAR T-cell activation and expansion: Simulation study with a virtual cell culture environment

This paper uses reinforcement learning to optimize CAR-T cell activation and expansion in a simulated cell culture environment, showing that PPO-tabular performs best for this task.

Characterizing the Interactions of Cell Membrane-Disrupting Peptides with Lipid-Functionalized Single-Walled Carbon Nanotube Systems for Antimicrobial Screening

This paper uses molecular dynamics simulations to study how three antimicrobial peptides interact with lipid-functionalized SWNTs, showing that they induce different structural perturbations in the lipid corona.

Design and Validation of a Frugal, Automated, Solid-Phase Peptide Synthesizer

The paper designs and validates a low-cost automated solid-phase peptide synthesizer using consumer-grade components, achieving a cost of about $1 per residue.

Simple, Functional, Inexpensive Cell Extract for in vitro Prototyping of Proteins with Disulfide Bonds

The paper presents a simple, inexpensive E. coli extract for in vitro expression of proteins with disulfide bonds, using a SHuffle T7 Express lysY strain and optimized conditions.

Controlling Heterogeneity and Increasing Titer from Riboswitch-Regulated Bacillus subtilis Spores for Time-Delayed Protein Expression Applications

This paper investigates how plasmid type and PolY mutations affect protein expression rates and variance in Bacillus subtilis spores, finding higher expression rates with plasmids but increased variance post-sporulation.