ImmunologybioRxivPreprint
Balance of AKT isoforms in intestinal barrier function. Implications for IBD therapy.
T. Garcia Prieto, A. Barbachano, N. G. Cuesta…·M. Fresno
This study shows that balancing Akt1 and Akt2 isoforms regulates intestinal barrier function and inflammation, with Akt2 inhibition improving IBD symptoms in mice.
DOI 10.1101/2023.07.04.547629