Author

N. G. James

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

D. M. Jameson· 2 shared A. Brideau-Andersen· 1 shared B. Barylko· 1 shared B. J. Sanstrum· 1 shared B. Jacky· 1 shared C. Rheaume· 1 shared C.-L. Chiu· 1 shared J. P. Albanesi· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

D. M. Jameson

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2 papers

Recent·Most cited

A mutation associated with Charcot-Marie-Tooth disease enhances the formation of stable dynamin 2 complexes in cells

P. N. Hedde, B. Barylko, C.-L. Chiu, J. P. Albanesi, D. M. Jameson, N. G. James

This study shows a CMT-causing DNM2 mutation, {Delta}DEE, fails to undergo auto-inhibition and forms cytoplasmic inclusions, similar to CNM mutants, challenging the current understanding of disease-specific mechanisms.

bioRxiv · Dec 13, 2021 · PreprintCell Biology

Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using a novel receptor dimerization assay

N. G. James, S. Malik, B. J. Sanstrum, C. Rheaume, R. S. Broide, D. M. Jameson, A. Brideau-Andersen, B. Jacky

This paper develops a receptor dimerization assay to study BoNT/A interactions with FGFRs, showing HC/A induces FGFR dimerization with potency varying by receptor subtype.

Scientific Reports · Apr 9, 2021Peer-reviewedCell Biology