Author

B. Jacky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Brideau-Andersen· 1 shared A. C. Chu· 1 shared A. D. Brideau-Andersen· 1 shared B. J. Sanstrum· 1 shared C. Rheaume· 1 shared D. C. Rupp· 1 shared D. M. Jameson· 1 shared E. J. Vazquez-Cintron· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Brideau-Andersen

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Author profile →

2 papers

Recent·Most cited

Reengineering the Specificity of the Highly Selective Clostridium botulinum Protease via Directed Evolution

R. P. Dyer, H. M. Isoda, G. S. Salcedo, G. Speciale, M. H. Fletcher, L. Q. Le, Y. Liu, S. Z. Malik, E. J. Vazquez-Cintron, A. C. Chu, D. C. Rupp, B. Jacky, T. T. Nguyen, L. E. Steward, S. Majumdar, , G. A. Weiss

This study uses directed evolution to reengineer the BoNT/A protease to target SNAP23, improving its cleavage specificity and catalytic efficiency for therapeutic applications.

bioRxiv · Sep 29, 2020Biochemistry

Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using a novel receptor dimerization assay

N. G. James, S. Malik, B. J. Sanstrum, C. Rheaume, R. S. Broide, D. M. Jameson, A. Brideau-Andersen, B. Jacky

This paper develops a receptor dimerization assay to study BoNT/A interactions with FGFRs, showing HC/A induces FGFR dimerization with potency varying by receptor subtype.

bioRxiv · Jul 29, 2019Cell Biology