Author

N. Gruel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Surdez· 2 shared I. Janoueix-Lerosey· 2 shared O. Delattre· 2 shared S. Baulande· 2 shared S. Durand· 2 shared S. Grossetete-Lalami· 2 shared S. Zaidi· 2 shared V. Boeva· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

D. Surdez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential predictive value of resident memory CD8+T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy

L. Paolini, T. Tran, S. Corgnac, J.-P. VILLEMIN, M. Wislez, J. Arrondeau, L. Johannes, J. Ulmer, L.-V. Vieillard, J. Pineau, A. Gey, V. Quiniou, P. Barennes, H. P. Pham, n. Gruel, , E. TARTOUR

The paper identifies two TRM subpopulations in NSCLC patients and shows that only DP TRM predicts response to PD-1 blockade immunotherapy.

bioRxiv · Mar 7, 2024Immunology

Interplay between intrinsic reprogramming potential and microenvironment controls neuroblastoma cell plasticity and identity

C. Thirant, A. Peltier, S. Durand, A. Kramdi, C. Louis-Brennetot, C. Pierre-Eugene, A. Costa, A. Grelier, S. Zaidi, N. Gruel, I. Jimenez, E. Lapouble, G. Pierron, H. Brisse, A. Gauthier, , I. Janoueix-Lerosey

This study shows that neuroblastoma cells can switch between noradrenergic and mesenchymal identities through epigenetic reprogramming, influenced by both intrinsic factors and the microenvironment.

bioRxiv · Jan 7, 2021 · PreprintCancer Biology

Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single cell resolution

M.-M. Aynaud, O. Mirabeau, N. Gruel, S. Grossetete-Lalami, V. Boeva, S. Durand, D. Surdez, O. Saulnier, S. Zaidi, S. Gribkova, U. Kairov, V. Raynal, F. Tirode, T. G. Grunewald, M. Bohec, , A. Zinovyev

This study identifies transcriptional programs driving intratumoral heterogeneity in Ewing sarcoma using single-cell RNA-sequencing and chromatin analysis.

bioRxiv · Apr 30, 2019Cancer Biology