Cytotoxic CD4 Development Requires CD4 Effectors to Concurrently Recognize Local Antigen and Encounter Infection-Induced IL-15
P. Devarajan, A. M. Vong, C. H. Castonguay, N. J. Silverstein, B. L. Bautista, O. Kugler-Umana, K. A. Kelly, J. Luban, S. L. Swain
This study identifies factors driving CD4 T cells to differentiate into cytotoxic lung-resident ThCTL during influenza infection.
bioRxiv · Sep 3, 2020Immunology