Author

S. L. Swain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Castonguay· 2 shared O. A. Kugler-Umana· 2 shared P. Devarajan· 2 shared A. M. Vong· 1 shared A. Marshak-Rothstein· 1 shared B. L. Bautista· 1 shared B. Stadinski· 1 shared C. H. Castonguay· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

C. Castonguay

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Peptide Avidity for TCR on CD4 Effectors Determines the Extent of Memory Generation

M. C. Jones, C. Castonguay, P. P. Nanaware, G. C. Weaver, B. Stadinski, O. A. Kugler-Umana, E. Huseby, L. J. Stern, P. J. Devarajan, S. L. Swain

This study shows that higher peptide antigen avidity for TCR on CD4 effector cells leads to increased memory cell generation and better protection against influenza rechallenge.

bioRxiv · May 9, 2022Immunology

IgD+ Age-Associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

O. A. Kugler-Umana, W. Zhang, Y. Kuang, J. Liang, C. Castonguay, S. L. Tonkonogy, A. Marshak-Rothstein, P. Devarajan, S. L. Swain

The paper identifies IgD+CD21-CD23- age-associated B cells as precursors of infection-induced B cells in aged mice, which provide protective antibody responses and can be induced by inactivated vaccines.

bioRxiv · Feb 4, 2022Immunology

Cytotoxic CD4 Development Requires CD4 Effectors to Concurrently Recognize Local Antigen and Encounter Infection-Induced IL-15

P. Devarajan, A. M. Vong, C. H. Castonguay, N. J. Silverstein, B. L. Bautista, O. Kugler-Umana, K. A. Kelly, J. Luban, S. L. Swain

This study identifies factors driving CD4 T cells to differentiate into cytotoxic lung-resident ThCTL during influenza infection.

bioRxiv · Sep 3, 2020Immunology