Catechol-Containing Compounds are a Broad Class of Amyloid Inhibitors: Redox State is a Key Determinant of the Inhibitory Activities
P. Velander, L. Wu, S. B. Hildreth, N. J. Vogelaar, B. Mukhopadhyay, S. Zhang, R. F. Helm, B. Xu
The paper identifies catechol-containing compounds as broad amyloid inhibitors and shows redox state determines their activity.
bioRxiv · Oct 8, 2020 · PreprintPharmacology & Toxicology