Loss of multiple enzyme activities due to the human genetic variation P284T in NADPH cytochrome P450 oxidoreductase
S. Parween, M. N. R. Velazquez, S. S. Udhane, N. Kagawa, A. V. Pandey
This study investigates the impact of the P284T variant in POR on cytochrome P450 enzyme activities, finding significant reductions in several key functions.
bioRxiv · May 20, 2019Pharmacology & Toxicology