Proximity-based activation of AURORA A by MPS1 potentiates error correction
N. Leca, F. Barbosa, S. Rodriguez-Calado, M. Moura, P. D. Pedroso, I. Pinto, A. E. Verza, T. Bange, C. E. Sunkel, M. Barisic, T. J. Maresca, C. Conde
This study identifies a proximity-based activation mechanism where MPS1 phosphorylates AURORA A kinase to enhance error correction during mitosis.
bioRxiv · Jun 11, 2024Cell Biology