Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation.
S. Leishman, N. M. Aljadeed, L. Qian, S. Cockcroft, J. Behmoaras, P. K. Anand
This study shows that fatty acid synthesis promotes NLRP3 inflammasome activation through palmitoylation of NLRP3, with no effect on AIM2 inflammasome activation.
bioRxiv · Oct 30, 2023Immunology