Author

N. M. Troy

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bosco· 1 shared A. C. Jones· 1 shared B. J. Holt· 1 shared D. Anderson· 1 shared D. Mallon· 1 shared M. Serralha· 1 shared P. G. Holt· 1 shared R. Hartmann· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. Bosco

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1 paper

Recent·Most cited

Rewiring of Th-memory-associated gene co-expression networks underlie immunotherapy-induced changes in symptom expression in mite-sensitised atopics

A. C. Jones, D. Anderson, N. M. Troy, D. Mallon, R. Hartmann, M. Serralha, B. J. Holt, A. Bosco, P. G. Holt

This study shows that immunotherapy induces rewiring of gene co-expression networks in Th-memory responses, leading to stable symptom control through integration of Th2, FOXP3/IL2, inflammation, and Type1-IFN signaling modules.

bioRxiv · Oct 31, 2019 · PreprintImmunology