Author

N. Matange

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. Yelpure· 1 shared M. Balachandran· 1 shared R. Vinchhi· 1 shared V. Patel· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

C. Yelpure

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2 papers

Recent·Most cited

Adaptive and maladaptive consequences of deregulation in a bacterial gene regulatory network

R. Vinchhi, C. Yelpure, M. Balachandran, N. Matange

This study investigates how mutations in mgrB affect trimethoprim resistance in E. coli and explores the role of negative feedback in the PhoQP system.

bioRxiv · Jan 30, 2023 · PreprintMicrobiology

Adaptation and Compensation in a Bacterial Gene Regulatory Network Evolving Under Antibiotic Selection

V. Patel, N. Matange

This study shows that E. coli evolves trimethoprim tolerance through PhoPQ de-repression and later resistance via DHFR mutations or cost compensation via RpoS inactivation, depending on antibiotic selection strength.

bioRxiv · Aug 31, 2021Microbiology