IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER
I. Sequeira, J. F. Neves, D. Carrero, Q. Peng, N. Palasz, K. Liakath-Ali, G. Lord, P. R. Morgan, G. Lombardi, F. M. Watt
This study shows that Krt76 loss in epithelial cells promotes carcinogenesis by enhancing Treg function and pro-inflammatory cytokines in mouse models and human OSCC.
bioRxiv · Apr 21, 2018Cancer Biology