Structural basis for tuning activity and membrane specificity of bacterial cytolysins
N. R. Shah, T. B. Voisin, E. S. Parsons, C. M. Boyd, B. Hoogenboom, D. Bubeck
This study investigates how bacterial cytolysins use cholesterol to selectively lyse cells by analyzing structural changes in intermedilysin bound to CD59.
bioRxiv · Jun 16, 2020Biochemistry